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• Allopurinol

  Allopurinol is an oral medication typically used to prevent uric acid and calcium oxalate stones in dogs. It is also used off-label to treat leishmaniasis and gout in dogs and other species. Side effects are uncommon but may involve stomach upset. Caution must be taken when allopurinol is used in conjunction with certain other medications. It should not be used in pets with liver or kidney dysfunction or in red-tailed hawks.

• Amitriptyline

  Amitriptyline is used off label and given by mouth to treat behavioral and pain disorders in dogs, cats, and occasionally birds. Common side effects include sedation, dry mouth, constipation, and urinary retention. This medication should not be used in pets sensitive to TCAs, seizures, or pets currently using MOIs or flea collars. If a negative reaction occurs, please call your veterinary office.

• Azithromycin

  Azithromycin is given by mouth or injection and is used on and off-label to treat a variety of infections. Give as directed. Common side effects include stomach upset. Do not use in pets that are sensitive to macrolide antibiotics. If a negative reaction occurs, please call your veterinary office.

• Carprofen

  Carprofen is used on and off label and is given by mouth in the form of a tablet to treat pain and inflammation. The most common side effects include vomiting, diarrhea, and decreased appetite. Do not use this medication in pets with bleeding disorders, in pets that are allergic to it or other NSAIDs in the same class, or in pets concurrently using corticosteroids or other NSAIDs. If a negative reaction occurs, please call your veterinary office.

• Chloramphenicol

  Chloramphenicol is given by mouth or injection and is used on and off-label to treat bacterial infections. Give as directed. Common side effects include vomiting, diarrhea, and decreased appetite. Do not use in pets with blood disorders, in pediatric or geriatric animals, or in pregnant or nursing females. If a negative reaction occurs, please call your veterinarian.

• Chlorpheniramine Maleate

  Chlorpheniramine maleate is given by mouth and is used off label to treat allergic conditions or as a mild sedative. Common side effects include sleepiness, although other side effects are possible. Do not use in pets that are allergic to it or other similar antihistamines, or pets that are undergoing allergy testing within 2 weeks. If a negative reaction occurs, please call your veterinary office.

• Clomipramine

  Clomipramine is given by mouth and is used on and off label to treat behavior disorders such as obsessive-compulsive disorders, anxiety, aggression, and urine marking. Common side effects include lack of appetite, vomiting, diarrhea, constipation, dry mouth, elevated liver enzymes, difficulty urinating, or tiredness. Do not use in pets that are allergic to it or other tricyclic antidepressants, in breeding males, in pets with a history of seizures, or concurrently with monoamine oxidase inhibitors such as amitraz flea collars. If a negative reaction occurs, please call your veterinary office.

• Colchicine

  Colchicine is given by mouth and is used off label to primarily treat amyloidosis and Shar-Pei fever. Give as directed by your veterinarian. Side effects are not well documented and may include nausea, vomiting, diarrhea, lack of appetite, skin rash, incoordination, severe tiredness, weakness, infections, bleeding, or bruising. Do not use in pets that are allergic to it or in pets with severe kidney, gastrointestinal, or heart disease. If a negative reaction occurs, please call your veterinary office.

• Diazepam

  Diazepam is given by mouth, injection, or into the rectum and is used off label to treat anxiety, seizures, tense muscles, or decreased appetite. Give as directed by your veterinarian. Side effects include sleepiness, increased appetite, incoordination, weakness, agitation, drooling, and aggression. Do not give to cats by mouth, and do not use in pets that are allergic to it or other benzodiazepines, or in pets with severe liver disease. If a negative reaction occurs, please call your veterinary office.

• Diphenhydramine

  Diphenhydramine is given by mouth or as an injection and is used on and off label to treat allergic reactions, motion sickness, and to induce sedation. Side effects include sleepiness, and less commonly dry mouth and gastrointestinal upset. Diphenhydramine should not be used in pets that are allergic to this medication and should be used cautiously in pets with glaucoma, enlarged prostate, thyroid or heart disease, or are lactating. If a negative reaction occurs, please call your veterinary office.